Toxic and drug-induced myopathies

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چکیده

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منابع مشابه

Toxic and drug-induced myopathies.

Drugs used for therapeutic interventions either alone or in combination may sometimes cause unexpected toxicity to the muscles, resulting in a varying degree of symptomatology, from mild discomfort and inconvenience to permanent damage and disability. The clinician should suspect a toxic myopathy when a patient without a pre-existing muscle disease develops myalgia, fatigue, weakness or myoglob...

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Drug-induced myopathies.

PURPOSE OF REVIEW Drug-induced muscle disorders are important causes of morbidity, but the risk-benefit profile of the incriminated drugs must be put into perspective. This review highlights some recent advances on statin-induced and antiretroviral drug-induced myopathies and calls attention to some less familiar myotoxic disorders. RECENT FINDINGS In statin myopathy, reduction of coenzyme Q ...

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Drug-induced myopathies.

The most common drugs currently in use that may cause myopathies were reviewed using the Medline database (U.S. National Library of Medicine, Bethesda, Maryland). Our review included results from epidemiologic and database surveys, clinical trials, and case reports. The clinical spectrum is wide, and presentations range from asymptomatic elevations in serum creatine phosphokinase levels to seve...

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Toxic myopathies.

PURPOSE This article reviews the most important muscle toxins, many of which are widely prescribed medications. Particular emphasis is placed on statins, which cause muscle symptoms in a relatively large proportion of the patients who take them. RECENT FINDINGS As with other toxic myopathies, most cases of statin-associated myotoxicity are self-limited and subside with discontinuation of the ...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 2009

ISSN: 0022-3050

DOI: 10.1136/jnnp.2008.168294